WebAug 1, 2006 · Response to chlorpromazine treatment may be associated with polymorphisms of the DRD2 gene in Chinese schizophrenic patients. Neurosci Lett … WebDec 23, 2024 · Chlorpromazine is a medication used to manage and treat schizophrenia, bipolar disorder, and acute psychosis. It is a member of the typical antipsychotics or neuroleptic medication category, also known as first-generation antipsychotics.
Chlorpromazine C17H19ClN2S - PubChem
WebMar 7, 2005 · The present study examines the correlation between these two polymorphisms and the therapeutic response to chlorpromazine, a typical … WebAug 16, 2010 · Like other typical antipsychotics, chlorpromazine works primarily by blocking dopamine D2 receptors and this action is commonly believed to be responsible for controlling the symptoms of schizophrenia. The main pharmacological activities of clozapine include balanced serotonin and dopamine antagonism (Ase et al., 1999). mtsu theatre major
The Role of Glutamatergic Gene Polymorphisms in the Clinical …
WebAug 16, 2010 · We found that the polymorphic marker, rs2975226, showed significant association of allele and genotype frequencies with response to clozapine (allele-wise: adjusted p=0.00404; genotype-wise: adjusted p=0.024), and that patients with the T allele had a better response to the drug. WebSep 29, 2024 · Chlorpromazine adalah antipsikotik golongan fenotiazin yang digunakan dalam tata laksana skizofrenia, gejala psikosis, mual dan muntah, intractable hiccups dan gangguan bipolar. Selain itu, chlorpromazine juga dapat digunakan untuk gangguan perilaku berat pada anak-anak. [1–3] Webpolymorphism, with 20% of Orientals and 3–5% of drugs mediated by CYP2C19 and CYP2D6. It is useful Caucasians being reported as PMs (2, 4). When ... Chlorpromazine is metabolized reported that interethnic differences in debrisoquine mainly by demethylation (metabolite: nor- and di- hydroxylation polymorphism (CYP2D6) might partly how to make slime with only soap