Cisplatin hplc
WebGemcitabine (Gem) and cisplatin (Cis) are currently being used for lung cancer treatment, but they are highly toxic in high dosages. This research aimed to develop a niosome formulation... WebKey Words:Oxaliplatin, RP-HPLC, UV detection, recovery, precise, 240nm INTRODUCTION Oxaliplatin is a platinum-based antineoplastic agent that is used in cancer chemotherapy. oxaliplatin is the platinum-containing complex similar to cisplatin. This agent was recently approved for use as a second line therapy in metastatic colorectal cancer.
Cisplatin hplc
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WebNov 1, 2005 · Although a number of methods have been described for the determination of cisplatin in human fluids by high-performance liquid chromatography (HPLC), there are … WebMar 1, 2024 · Cisplatin is a platinum containing compound used for the treatment of different types of cancers. Quantitative determination of cisplatin has been carried out using atomic absorption spectroscopy, high pressure liquid chromatography with phosphorescence, ultra-violet detection, or with inductively coupled plasma mass …
WebCisplatin is a chemotherapy drug which is used to treat cancers including: sarcoma, small cell lung cancer, germ cell tumors, lymphoma, and ovarian cancer. While it is often … WebFeb 28, 2024 · Gold nanoparticles enhance cisplatin delivery and potentiate chemotherapy by decompressing colorectal cancer vessels. Xiaoxu Zhao 1 Department of General Surgery, ... HPLC analysis detected high concentrations of cisplatin in tumors after combined therapy, both of which indicated that the delivery efficacy of cisplatin was …
WebCisplatin, cis-diamminedichlorido-platinum(II), is an important therapeutic tool in the struggle against different tumors, yet it is plagued with the emergence of resistance mechanisms after repeated WebMar 1, 2024 · Cisplatin (Platinol ®) is a chemotherapeutic agent, first approved by the U.S. Food and Drug Administration (FDA) in 1978 for the treatment of ovarian cancer and finds its use nowadays for the treatment of various types of cancer including cervical cancer, testicular cancer and germ cell tumors [1].
WebA potent platinum-based antineoplastic drug. Its mode of action involves formation of inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. Platinated DNA adducts also enhance poisoning of DNA topoisomerase I. Cisplatin synergizes with a variety of anticancer agents.
WebFeb 26, 2015 · Cisplatin and apigenin were purchased from Sigma-Aldrich (St. Louis, MO, USA). All other reagents were of analytical grade or HPLC grade, and were obtained from DIMA Technology, Inc. (Richmond Hill, GA, USA). Analytical procedures. Cisplatin was separated by HPLC using a Symmetry C18 column (50×2.1 mm; Waters Corporation, … siamese vs gated wyeWebApr 1, 2012 · The HPLC method was developed using C 18 ODS Hypersil column of 250 × 4.6 mm id with 5 µm particle size, mobile phase of water : methanol : acetonitrile (40:35:25, v/v/v, pH 3.5) at a flow rate... siamese twins (the monkey and me)WebCisplatin - CAS 15663-27-1, is a platinum coordination complex with potent anti-neoplastic activity. Induces apoptosis in cancer cells, possibly via caspase-3 activation. Synonym (s): Cisplatin, CPDC, DDP, cis-Diaminedichloroplatinum Linear Formula: Pt (NH3)2Cl2 CAS Number: 15663-27-1 MDL number: MFCD00011623 NACRES: NA.77 the penalty shot shall be taken from handballWebA high-performance liquid chromatographic (HPLC) method is described for the determination of residual levels of cisplatin from extracts of surfaces with very low surface area; from extracts of surfaces of coupons made of Teflon (polytetrafluoroethylene, PTFE), stainless steel, and glass; and in aqu … siamese warningWebCisplatin Synonyms: cis-Diammineplatinum (II) dichloride, cis-Dichlorodiammine platinum (II), cis-Platinum (II) diammine dichloride, Cisplatin Linear Formula: Pt (NH3)2Cl2 CAS Number: 15663-27-1 Molecular Weight: 300.05 EC Number: 239-733-8 Product Comparison Guide Use the product attributes below to configure the comparison table. the penalty of prision mayorWebSep 15, 2024 · Cisplatin Injection (cisplatin injection (cisplatin (cisplatin injection) injection) ) is a sterile aqueous solution, available in 50, 100 and 200 mL multiple dose … the penalty function methodWebThe platinum content (4.91%) of Polycisplatin was determined by modified HPLC–UV method detailed in the literature. 19 Briefly, a known amount of Polycisplatin was dissolved in 0.5 M HCl solution and stirred so as to cleave the AA-Pt bond and release the cisplatin. The cisplatin was then treated with 100 µL of (10%) DDTC in 0.1 N NaOH and ... siamese vs thai cat