Cisplatin vp16
WebAbstract Purpose: Cisplatin (CDDP) and etoposide (VP16) are considered major standard cytotoxic drugs for small cell lung cancer (SCLC). The present systematic review had as its objective the evaluation of their role, as components of chemotherapy regimens, on survival. WebNov 17, 2012 · Cisplatin combined with oral VP16 is well tolerated and has acceptable side effects, but limited clinical activity in refractory/relapsed ESFT. Phase II trials …
Cisplatin vp16
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WebJan 17, 2024 · a Hydration is required with supplemental electrolytes pre- and post-administration of Cisplatin. b Cisplatin contraindicated or not tolerated. WebOct 7, 1992 · Purpose: A phase II study that used combination chemotherapy with carboplatin (CBDCA) and etoposide (VP 16) (CE) was performed on patients with recurrent malignant glioma to investigate tumor control and toxicity. Patients and methods: Thirty-eight patients were treated with CBDCA 300 mg/m2 on days 1 to 3 and VP 16 100 mg/m2 on …
WebCisplatin is a chemotherapy drug which is used to treat cancers including: sarcoma, small cell lung cancer, germ cell tumors, lymphoma, and ovarian cancer. While it is often … WebOral etoposide (VP16) in platinum-resistant epithelial ovarian cancer (EOC) This phase II study evaluates the efficacy and toxicity of a prolonged schedule second-line and third-line treatment of oral VP16 in patients with measurable advanced ovarian cancer resistant to, or relapsed following, platinum-based chemotherapy.
WebSep 18, 2024 · National Center for Biotechnology Information WebMar 23, 2015 · The recommendation to administer gemcitabine prior to cisplatin is based on results of phase 1 studies in adults with solid tumors, which indicated that this administration schedule may increase ...
WebThe cisplatin-VP16 (PE) regimen was used in 13 pts, and 9 of them (69%) obtained objective responses after chemotherapy (CT) alone, with 3 complete remissions (CR) and 6 partial remissions (PR). Median CR and PR duration was 13+ and 24 months, respectively. Radiotherapy was performed in 7/13 pts after induction CT and before consolidation CT.
WebJun 9, 2024 · About: Etoposide (Toposar®, VePesid®, Etopophos®,VP-16) Etoposide works by blocking the action of an enzyme in cells called topoisomerase, which is necessary for cell replication and tumor growth. Cells need this enzyme to keep their DNA in the proper shape when they are dividing. theraband cartWebThirty-one patients with small-cell lung cancer (SCLC) were treated with VP-16 and cisplatin as first-line therapy. In the majority of cases an Adriamycin (Adria Laboratories, … sign in to my pc matic accountWeb<45 Hold CISplatin or delay with additional IV fluids *Due to the curative intent of this chemotherapy regimen, in cases where CrCl falls between 45-59ml/min it may be appropriate to maintain dose of CISplatin but with extra hydration, longer infusion time and daily Creatinine measurements at the discretion of the prescribing consultant. theraband calf exercisesWebThe combinations: Cyclophosphamide/Doxorubicin/Methotrexate/Procarbazine, Cyclophosphamide/Doxorubicin/Cisplatin or Vindesine/Cisplatin are considered most prospective, were remission rates are reported to range from 30-40% with a mean period of remission from 5-7 months. theraband chair exercises pdfWebEtoposide (VP-16) and cisplatin: an effective treatment for relapse in small-cell lung cancer. Seventy-eight patients with evaluable small-cell lung cancer (SCLC) were treated with … theraband chemisthttp://www.bccancer.bc.ca/chemotherapy-protocols-site/Documents/Lung/LUSCPE_Protocol.pdf sign in to my ps4 accountWebSep 25, 2024 · Standard-of-care first-line treatment for extensive-stage small-cell lung cancer is platinum chemotherapy (carboplatin or cisplatin) with etoposide. 1-3 Despite response rates of 60 to 65%,... theraband chair exercises