WebJan 21, 2024 · CypD MEDIATES HEPATIC TG ACCUMULATION BY UP-REGULATING SREBP-1c. To explore the mechanism of CypD-induced … WebJun 1, 2014 · Program Director/Principal Investigator: Du, Heng Project Description/Abstract Mitochondrial dysfunction and synaptic loss are early pathological features of Alzheimer's …
Early deficits in synaptic mitochondria in an Alzheimer s …
WebJan 22, 2024 · CypD KO mice were obtained from professor Heng Du (The University of Texas, Dallas). Information of these mice were described in our previous research [16]. … WebMay 9, 2024 · CypD stimulates mPTP excessive opening, subsequently causing endoplasmic reticulum stress through p38 mitogen-activated protein kinase activation, and results in enhanced sterol regulatory element-binding protein-1c transcription and hepatic steatosis. (Hepatology 2024;68:62-77). Full text links north high school denver co
Berberine improves intralipid-induced insulin resistance in …
WebJan 22, 2024 · CypD is the well accepted modulator for mitochondrial permeability transition pore (mPTP) activation [ 18 ]. We firstly adopted Ca 2+ -overload induced mitochondrial swelling to observe mPTP activation in the aorta of mouse models. WebEarly deficits in synaptic mitochondria in an Alzheimer’s disease mouse model Heng Dua,1, Lan Guoa,1, Shiqiang Yana,2, Alexander A. Sosunovb, Guy M. McKhannb, and Shirley ShiDu Yana,c,d,3 Departments of aSurgery, bNeurosurgery, and cPathology and Cell Biology, and dThe Taub Institute for Research on Alzheimer’s Disease and the … WebMar 8, 2024 · CypD is a key component of mitochondrial permeability transition pore. Under stresses, CypD associates with the adenine nucleotide translocase(ANT) in the inner … north high school evansville in