High glucose macrophage
WebHigh glucose contributes to the polarization of peritoneal macrophages to the M2 phenotype in vivo and in vitro. Glucose is the primary osmotic medium used in most … Web29 de jun. de 2024 · Here we show that LPS stimulation of RAW264.7 macrophage cells cultured in high glucose medium leads to pyroptosis, which can be suppressed by a …
High glucose macrophage
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Web1 de dez. de 2008 · High glucose increases lipoteichoic acid stimulated MMP 9 secretion in RAW 264.7. RAW 264.7 macrophages were incubated with normal or increased glucose concentrations (plus 150 or 300 mg/dl) for 48 h. In the last 24 h, the incubation medium was changed and, when indicated, LTA (1 μg/ml) was added. Web25 de mar. de 2015 · The present study investigates the effect of 1,25-dihydroxyvitamin D 3 on macrophage activation state and its underlying mechanism in RAW264.7 cells. We find that, under high glucose conditions, RAW264.7 macrophages tend to switch to the M1 phenotype, expressing higher iNOS and proinflammatory cytokines, including TNF α and …
Web30 de mar. de 2024 · High fructose diet induces macrophage recruitment in adult heart. (A) Heart tissue was stained with F4/80 antibody by ... et al. No differential effect of beverages sweetened with fructose, high-fructose corn syrup, or glucose on systemic or adipose tissue inflammation in normal-weight to obese adults: a randomized controlled trial ... Web20 de jan. de 2024 · As shown in Figure 1A, macrophage-derived exosomal MALAT1 significantly increased from 12.5 mM to 50 mM of glucose concentration, and 25 mM high glucose had the maximal effect. Therefore, 25 mM high glucose was …
WebHDL-mediated cholesterol efflux from macrophages was significantly increased by 350% on using macrophages incubated with high glucose in the presence of insulin, compared to macrophages incubated only with glucose (18 ± 2% HDL-mediated cholesterol efflux from macrophages incubated with high glucose in the presence of insulin and 4 ± 2% in … Web11 de jul. de 2024 · Long-term high glucose treatment reduced macrophage glycolytic capacity and glycolytic reserve without affecting mitochondrial ATP production …
Web1 de abr. de 2024 · MAIT cell inhibition reduces inflammatory and fibrogenic genes in human PCLS. We evaluated the consequences of MAIT cell inhibition on liver fibrogenesis in human liver samples, using ex vivo PCLS ...
Web17 de ago. de 2024 · In the present study, we examined the impact of hyperglycemia on macrophage pro-inflammatory responses under an inflammatory stimulus. To conduct this study, RAW264.7 macrophages were cultured under normal- (5.5 mM) or high-glucose (22 or 40 mM) conditions for 7 days and stimulated with lipopolysaccharide (LPS). photo edit with text fontWeb7 de ago. de 2024 · High glucose levels appear to modify macrophage behaviour, affecting different aspects of diabetic and healthy BMDMs under the same LPS stimulus. Thus, hyperglycaemia leaves a glucose legacy ... how does deforestation affect rainforestsWeb27 de ago. de 2024 · Multi-omics analysis identifies potential mechanisms by which high glucose accelerates macrophage foaming Jie Qi, Ying Lv, Ni-Er Zhong, Wen-Qi Han, Qi-Ling Gou & Chao-Feng Sun Molecular and Cellular Biochemistry 478 , 665–678 ( 2024) Cite this article 384 Accesses 5 Altmetric Metrics Supplementary Information how does deforestation affect the spheresWeb27 de mar. de 2024 · In addition, autophagy blockade by high glucose via the mTOR-ULK1 pathway led to severe oxidative stress response in macrophages stimulated by … photo edit trialWeb12 de abr. de 2024 · Chronic non-healing wounds, a prevalent complication of diabetes, are associated with increased mortality in diabetic patients. Excessive accumulation of M1 macrophages in diabetic wounds promotes inflammation and results in dysregulated tissue repair. Adipose tissue macrophages (ATMs) derived from healthy lean donors have the … photo editing 1080p vss 4kWeb5 de mai. de 2024 · Murine macrophages were cultured in a high‑glucose in vitro environment, and the percentage of M1 macrophages in 138.8 mmol/l glucose medium … how does deforestation benefit humansWebOur findings suggested that high glucose activated macrophages mainly in TAK1/MAPKs and TAK1/NF-κB-dependent manners, which lead to the polarization of macrophages … photo editing 18