WebExpression of COX-2 resulted from an increase in mRNA stability via its 3'-untranslated region (UTR), shown by COX-2-3'-UTR and AU-rich element-driven reporter assays. … Web6 apr. 2024 · Our data suggest that SLBP degrades under stress, destabilizing the stem-loop, elongating histone isoforms mRNA with 3′ polyadenylated tail with increase of HuR …
LncRNA AC006064.4–201 serves as a novel molecular marker in …
Web11 jul. 2024 · RNA-binding protein (RBP) has a highly dynamic spatiotemporal regulation process and important biological functions. They are critical to maintain the transcriptome … WebHuR is the ubiquitous member of the Hu RBP family and acts mainly as a positive regulator of mRNA stability, partially by competing with ARE-binding RBPs, such as TTP and … how many syns can i have on slimming world
Regulation and function of poised mRNAs in lymphocytes
WebHypoxic Stabilization of Vascular Endothelial Growth Factor mRNA by the RNA-binding Protein HuR. DOI Web Site Web Site Web Site 被引用文献11 ... WebThe 5′UTR contains regulatory sequences encoded in the DNA and chemical modifications such as the addition of a 7-methyl-Guanosine (7mG) cap that binds regulatory proteins.40Working together with cap-independent mechanisms and structural remodelling of 5′UTRs these may facilitate dynamic regulation of poised mRNAs. WebBoth receptors are upregulated upon vascular injury but the underlying mechanisms have not been defined. We examined if FXa regulates PAR-1 and PAR-2 in human vascular SMCs. FXa increased PAR-2 mRNA, protein, and cell-surface expression and augmented PAR-2-mediated mitogenesis. PAR-1 was not influenced. how many syns in a banana slimming world