WebbPreparation of Zn(OPiv) 2 Pivalic acid (20.4 g, 22.6 mL, 200 mmol) was placed in a dry and argon-flushed 500 mL three-necked round-bottom flask, equipped with a magnetic stirring bar, a septum and a pressure equalizer, and was dissolved in dry THF (120 mL). The mixture was cooled at 0 °C, Webbpage 2 of 2 that repeating our optimized conditions (Entry 6, Table 1) with no catalyst produced no product of any kind, confirming the role of the dirhodium metal in aziridination. Entry Oxidant Equiv. Solvent Temp (ºC) Time (h) Result 1 PhI(OAc) 2 1.2 CH 2 Cl 2 50 1 28% isolated yield 2 PhI(OPiv) 2 1.2 CH 2 Cl 2

Scope and Mechanism of Allylic C−H Amination of Terminal …

Webb2 R f 1a 4 PhI(OPiv) 2 (1.5 equiv) R f CH 2 OH , 20 min, 50 o C H Amide 1a (0.2 mmol), PhI(OPiv)2 (1.5 equiv) and fluoroethanol (8.0 equiv) were combined in a 10 mL tube. The mixture was then stirred at 50 oC for 20 min. After the conversion was completed as indicated by TLC, the mixture was diluted with water and extracted with EA. The collected WebbTable 1. The use of Cu(OPiv) 2 as metal catalyst improved the yield to 42% (Entry 2), while Cu(OTf) 2 was not able to catalyze the reaction (Entry 3). Addition of 1 equiv. of Zn(OPiv) 2 (Entry 4) or Mg(OPiv) 2 (Entry 5) decreased the yield, yet 1 equiv. of Mg(OPiv) 2 and H 2Oslightly increasedthe yieldto 44%(Entry 6). Notably,theadditionofH how to scan and upload a pdf file

New Methods for Nitrene Generation and Transfer in the Selective ...

WebbCAS Number: 51364-51-3 Molecular Weight: 915.72 MDL number: MFCD00013310 PubChem Substance ID: 24859746 NACRES: NA.22 Pricing and availability is not … Webb30 dec. 2009 · 上海有机所的刘国生和吴涛等研究人员首次发现在钯的催化下，利用AgF作为氟源，PhI (OPiv) 2 为氧化剂，可以实现烯烃的分子内的氟胺化反应。. 该反应以很好的化学选择性和区域选择性得到含氟的六元含氮杂环，这类化合物目前被广泛应用于药物化学的研 … WebbIntramolecular oxyacetoxylation of N-allylamides: an expeditious synthesis of oxazolines and oxazines by using a PhI(OAc) 2 /hydrogen fluoride–pyridine system. Organic & Biomolecular Chemistry 2016 , 14 (42) , 10074-10079. how to scan and then email