WebAug 24, 2024 · Given the role of Pomp in late stage proteasome formation and maturation 13, 30, we performed siRNA-mediated Pomp knockdown and measured immunoproteasome assembly following IFNγ treatment. WebApr 4, 2024 · The proteasome is a macromolecular proteolytic machine in charge of controlled degradation of proteins ().The proteasome core, also known as the 20S …
siRNA Silencing of Proteasome Maturation Protein (POMP) …
WebOct 19, 2007 · There, POMP recruits the remaining β-subunits into the nascent complex and supports the final proteasome maturation . Such a POMP-mediated model allows for … WebPOMP (proteasome maturation protein) LOVD v.3.0 Build 29 [ Current LOVD status] Register as submitter Log in : Curator: Global Variome, with Curator vacancy: View all genes; View … sparrow serving
Human filaggrin monomer does not seem to be a proteasome target
WebJul 16, 2015 · Inhibiting POMP and 20S assembly without blocking subunit expression must significantly increase the cellular content of aggregation-prone free subunits, further … WebNX_Q9Y244 - POMP - Proteasome maturation protein - Function. Molecular chaperone essential for the assembly of standard proteasomes and immunoproteasomes. Degraded … WebAug 3, 2024 · POMP is a chaperone for proteasome assembly and is critical for proteasome incorporation. Interestingly, a recent report published by a US group stated that mutations of PSMG2, encoding for another proteasome chaperone called PAC2, could also cause CANDLE . The clinical manifestations of PRAAS are diverse. techmart computer products