Prolyl 4-hydroxylase subunit alpha 2
WebOct 11, 2001 · The best characterized prolyl-4-hydroxylases modify collagen as it matures along the exocytotic pathway . These enzymes are typically composed of two α and two β subunits, with the α subunit responsible for the prolyl hydroxylase activity. Three lines of evidence rule out these enzymes as the HIF prolyl hydroxylase. WebAug 13, 2024 · Results: The current study showed that P4HAs were highly expressed in BC patients with clinical stage I compared with nontumor control and elevated P4HAs were correlated with poor survival outcomes. Subtypes analysis revealed that P4HA1 and P4HA2 were most expressed in HER2+ subtypes patients.
Prolyl 4-hydroxylase subunit alpha 2
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WebProlyl 4-hydroxylase subunit alpha-2 EC number EC:1.14.11.2 ( UniProtKB ENZYME Rhea) 1 publication Short names 4-PH alpha-2 Alternative names Procollagen-proline,2 … WebThis gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is …
WebJan 14, 2011 · The alpha(I) and alpha(II) subunits do not form a mixed alpha(I)alpha(II)beta2 tetramer. J Biol Chem. 1997 Jul 11;272(28):17342-8. Nokelainen M, Nissi R, Kukkola L, Helaakoski T, Myllyharju J: Characterization of the human and mouse genes for the alpha subunit of type II prolyl 4-hydroxylase. WebGene ID: 128050340, updated on 28-Feb-2024. Summary Other designations. prolyl 4-hydroxylase subunit alpha-2
WebMay 19, 2024 · Cloning, baculovirus expression, and characterization of a second mouse prolyl 4-hydroxylase alpha-subunit isoform: formation of an alpha 2 beta 2 tetramer with the protein disulfide-isomerase/beta subunit. ... Prolyl-4-hydroxylase Α subunit 2 (P4HA2) expression is a predictor of poor outcome in breast ductal carcinoma in situ (DCIS). Webアズワンの【AXEL】84-2226-49 P4HA2 (Prolyl 4-hydroxylase Subunit alpha-2) 100ul 212449のコーナーです。AXELは研究開発、医療介護、生産現場、食品衛生など幅広い …
WebApr 24, 2024 · In addition to the down-regulation of elastin, we found up-regulation of druggable enzymes and regulators such as the long non-coding RNA H19, inter-alpha …
WebJan 14, 2011 · Procollagen-proline 4-dioxygenase activity Specific Function Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. Pfam Domain Function 2OG-FeII_Oxy ( PF03171) P4Ha_N ( PF08336) Transmembrane Regions Not Available Cellular Location Endoplasmic reticulum lumen … dremel rotary toolsWebProtein target information for Prolyl 4-hydroxylase subunit alpha-1 (chicken). Find diseases associated with this biological target and compounds tested against it in bioassay … english honeycomb class 7WebProtein target information for Prolyl 4-hydroxylase subunit alpha-1 (chicken). Find diseases associated with this biological target and compounds tested against it in bioassay experiments. dremel scroll saw price egyptWebアズワンの【AXEL】84-5022-62 P4HA2 (Prolyl 4-hydroxylase Subunit Alpha-2, Prolyl 4-hydroxylase, Alpha Polypeptide II) 100ul 487941のコーナーです。AXELは研究開発、医療介護、生産現場、食品衛生など幅広い分野に750万点以上の品揃えでお応えする商品サイト。3000円以上ご注文で送料無料。 english homes for rentWebOct 1, 2024 · In this study, we assessed the effect of HIF1α enhancement using prolyl hydroxylase inhibitor ( PHD ‐I) DMOG, on a key profibrotic marker of kidney disease. In specific, we examined the change in expression of Collagen 4 subunit A2 in cultured urinary cells of CKD patients pre and post 24‐hour exposure to 1mM DMOG. dremel scroll saw air bellowsWebProlyl 4-hydroxylases (P4Hs) have central roles in the synthesis of collagens and the regulation of oxygen homeostasis. The 4-hydroxyproline residues generated by the endoplasmic reticulum (ER) luminal collagen P4Hs (C-P4Hs) are essential for the stability of the collagen triple helix. dremel shoe polisher partsdremel scribe tool