Stathmin-3

Author: ntdh

August undefined, 2024

WebOct 1, 2004 · Stathmin is the founding member of a family of proteins that play critically important roles in the regulation of the microtubule cytoskeleton. Stathmin regulates microtubule dynamics by promoting depolymerization of microtubules and/or preventing polymerization of tubulin heterodimers. Upon entry into mitosis, microtubules polymerize … WebJun 9, 2016 · The Golgi apparatus is a highly dynamic cellular organelle that ensures the processing and sorting of proteins form their site of synthesis in the endoplasmic reticulum (ER) en route to their final destination, which is reflected by its functional division into a cis (entry) side and a trans (exit) side.

Stathmin as a surrogate marker of phosphatidylinositol-3 …

WebMar 21, 2024 · STMN2 (Stathmin 2) is a Protein Coding gene. Diseases associated with STMN2 include Trichorhinophalangeal Syndrome, Type Ii and Creutzfeldt-Jakob … WebMar 26, 2024 · Additionally, sALS patients and controls exhibited variable expression of Stathmin-2 mRNA according to CA genotype in laser-captured spinal motor neurons. Conclusions: We report a novel non-coding CA repeat in Stathmin-2 which is associated with sALS disease risk and has disease modifying effects. The potential value of this variant … man city vs fc bayern

STMN3 protein expression summary - The Human Protein Atlas

WebIntroduction: Stathmin is a microtubule-destabilizing phosphoprotein, firstly identified as the downstream target of many signal transduction pathways. Several studies then indicated … WebStathmin-3 Gene Stmn3 Status UniProtKB reviewed (Swiss-Prot) Organism Mus musculus (Mouse) Amino acids 180 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Add a publication Entry feedback Function WebJan 18, 2024 · This study established the critical role of TDP-43 in RNA processing within motor neurons and showed that known ALS-associated mutations in TDP-43 dysregulate hundreds of its RNA targets, including stathmin-2. Specifically, TDP-43 depletion in the nucleus leads to aberrant splicing and premature polyadenylation of stathmin-2. man city v sevilla

Novel STMN2 Variant Linked to Amyotrophic Lateral Sclerosis Risk and …

The role of stathmin in the regulation of the cell cycle

WebApr 6, 2024 · About STATHMIN-2 and TDP-43 STATHMIN-2 (STMN2) is a well-validated protein important for neural repair and axonal stability, the expression of which is significantly decreased in nearly all ALS ... WebOct 19, 2011 · Even though Stathmin is prominently expressed in the peripheral glia surrounding motoneuron axons, expression of stathmin RNAi by the pan-glial repo-Gal4 driver does not reduce bouton number at muscle 4 NMJs (wild type, 21.4 ± 1.3 boutons per NMJ; stathmin RNAi, 23.0 ± 1.0 boutons per NMJ, n = 22 NMJ each; p > 0.3) and results in … koordinationstraining ballWebAug 5, 2024 · STMN3 stathmin 3 [ (human)] Gene ID: 50861, updated on 5-Aug-2024 Summary This gene encodes a protein which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. man city vs ipswich

"WebAbstract. Rat pheochromocytoma PC12 cells have been widely used to investigate the neurotrophic activities of pituitary adenylate cyclase-activating polypeptide (PACAP). In … " - Stathmin-3

Stathmin-3

Stathmin as a surrogate marker of phosphatidylinositol-3 …

WebResults: Stathmin 3 displays specific phosphorylation patterns by ERK2 and CDK5 and is a unique stathmin substrate for glycogen synthase kinase 3 mostly at neurite tips. Conclusion: Stathmin proteins can be specifically and locally regulated by proline-directed phosphorylation. WebTitle: Specific serine-proline phosphorylation and glycogen synthase kinase 3β-directed subcellular targeting of stathmin 3/Sclip in neurons. Studies suggest that a STAT3-SCLIP …

Did you know?

WebAbstract. Background/Aims: Several recent studies have demonstrated that Stathmin 1expression may be closely associated with prognosis in patients with various types of cancers. In the present study, we conducted a meta-analysis of all available studies in the English literature to assess the prognostic value of Stathmin 1expression in patients with … http://www.neobioscience.com/prod_view.aspx?TypeId=409&Id=2337947&FId=t3:409:3

WebBackground: Stathmin-1 regulates microtubule dynamics and is associated with malignant phenotypes in non-small cell lung cancer (NSCLC). This study evaluated its diagnostic … WebOct 19, 2024 · Recently, this TDP-43 suppressor function was specifically implicated in suppressing a cryptic early polyadenylation site in the pre-mRNA for the protein stathmin-2 (STMN2). Loss of TDP-43 allows incorporation of a premature poly A tail, resulting in a truncated and nonfunctional form of STMN2 ( 15, 16 ).

WebSep 9, 1997 · Stathmin is an important regulatory protein thought to control the dynamics of microtubules through the cell cycle in a phosphorylation-dependent manner. Here we … Webstathmin-3, SCG10-like protein, SCG10-related protein HiAT3, Scgn10 like-protein, hippocampus abundant transcript 3. GeneRIFs: Gene References Into Functions. The determined the genomic and promoter structures of the SCLIP gene, and found that the gene retained an NRS-like element that functioned as a negative regulator in non-neuronal cells. …

WebMar 29, 2024 · Official Full Name stathmin 2 provided by HGNC Primary source HGNC:HGNC:10577 AllianceGenome:HGNC:10577 Gene type protein coding RefSeq status Organism Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; … man city vs fc bayern scoreWebOct 1, 2004 · Stathmin is the founding member of a family of proteins that play critically important roles in the regulation of the microtubule cytoskeleton. Stathmin regulates … man city vs leicester live stream redditWebThese data support a stathmin-dependent pathway of As2O3-mediated cell death in solid tumor cells, and indicate that stathmin is a target of the PI3K/Akt pathway in cervical cancer cells. All these results may provide a rationale for improving the efficacy of As2O3 as a therapeutic agent through combination treatment with stathmin inhibition or ... man city vs lcfcWebFeb 22, 2010 · Stathmin, a microtubule-destabilizing protein, is dysregulated in spinal muscular atrophy† Human Molecular Genetics Oxford Academic Abstract. Spinal muscular atrophy (SMA), a motor neuron degeneration disorder, is caused by either mutations or deletions of survival motor neuron 1 (SMN1) gene man city v sheffield unitedStathmin-3 is a protein that in humans is encoded by the STMN3 gene. man city vs fulham f.cWebMar 21, 2024 · STMN1 (Stathmin 1) is a Protein Coding gene. Diseases associated with STMN1 include Acute Leukemia and Leukemia . Among its related pathways are Signaling by ERBB4 and ERK Signaling . Gene … man city vs leeds predicted line upWebJan 23, 2002 · It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and … koordinationstraining definition